Skip to Content
Merck

WNT3

wingless-type MMTV integration site family, member 3

Synonyms:
INT4
Species:
UniProtKB ID:
Gene ID:
  • Human(7473) Summary: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region. [provided by RefSeq, Jul 2008]
  • Mouse(22415) wingless-related MMTV integration site 3
  • Rat(24882) wingless-type MMTV integration site family, member 3
  • Zebrafish(569420) wingless-type MMTV integration site family, member 3
  • Horse(100049880) wingless-type MMTV integration site family, member 3
  • domestic cat(101088533) wingless-type MMTV integration site family, member 3
  • dog(609107) wingless-type MMTV integration site family, member 3
  • chicken(374142) wingless-type MMTV integration site family, member 3
  • domestic guinea pig(100734613) wingless-type MMTV integration site family, member 3
  • Domestic Rabbit(100009033) wingless-type MMTV integration site family, member 3
  • naked mole-rat(101724651) wingless-type MMTV integration site family, member 3
  • cow(540753) wingless-type MMTV integration site family, member 3
  • sheep(101120096) wingless-type MMTV integration site family, member 3

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-WNT3 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-Wnt3 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human WNT3,
Species
human