SCN4A
sodium channel, voltage-gated, type IV, alpha subunit
Synonyms:
HOKPP2, HYKPP, HYPP, NAC1A, Na(V)1.4, Nav1.4, SkM1
Species:
Human SCN4A (6329), Mouse Scn4a (110880), Rat Scn4a (25722), domestic guinea pig Scn4a (100717730), naked mole-rat Scn4a (101713228), cow SCN4A (517426), sheep SCN4A (101123056), chicken SCN4A (771297), Horse SCN4A (100049793), domestic cat SCN4A (101098669)
UniProtKB ID:
Gene ID:
- Human(6329) Summary: Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. It is expressed in skeletal muscle, and mutations in this gene have been linked to several myotonia and periodic paralysis disorders. [provided by RefSeq, Jul 2008]
- Mouse(110880) sodium channel, voltage-gated, type IV, alpha
- Rat(25722) sodium channel, voltage-gated, type IV, alpha subunit
- domestic guinea pig(100717730) sodium channel, voltage-gated, type IV, alpha subunit
- naked mole-rat(101713228) sodium channel, voltage-gated, type IV, alpha subunit
- cow(517426) sodium channel, voltage-gated, type IV, alpha subunit
- sheep(101123056) sodium channel, voltage-gated, type IV, alpha subunit
- chicken(771297) sodium channel, voltage-gated, type IV, alpha subunit
- Horse(100049793) sodium channel, voltage-gated, type IV, alpha subunit
- domestic cat(101098669) sodium channel, voltage-gated, type IV, alpha subunit
- dog(610754) sodium channel, voltage-gated, type IV, alpha subunit
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SCN4A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Monoclonal Anti-Sodium Channel, Pan antibody produced in mouse, ~1 mg/mL, clone K58/35, purified immunoglobulin,
Species Reactivity
mammals
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Blocker
Product Number
Description
Species
Phenytoin solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Phenytoin for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human