PDE1B
phosphodiesterase 1B, calmodulin-dependent
Synonyms:
PDE1B1, PDES1B
Species:
Human PDE1B (5153), Mouse Pde1b (18574), Rat Pde1b (29691), Domestic Rabbit PDE1B (100341084), naked mole-rat Pde1b (101718122), domestic guinea pig Pde1b (100527959), cow PDE1B (281970), sheep PDE1B (101118773), dog PDE1B (100856025), Horse PDE1B (100064711)
UniProtKB ID:
Gene ID:
- Human(5153) Summary: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
- Mouse(18574) phosphodiesterase 1B, Ca2+-calmodulin dependent
- Rat(29691) phosphodiesterase 1B, calmodulin-dependent
- Domestic Rabbit(100341084) phosphodiesterase 1B, calmodulin-dependent
- naked mole-rat(101718122) phosphodiesterase 1B, calmodulin-dependent
- domestic guinea pig(100527959) phosphodiesterase 1B, Ca2+-calmodulin dependent
- cow(281970) phosphodiesterase 1B, calmodulin-dependent
- sheep(101118773) phosphodiesterase 1B, calmodulin-dependent
- dog(100856025) phosphodiesterase 1B, calmodulin-dependent
- Horse(100064711) phosphodiesterase 1B, calmodulin-dependent
- domestic cat(101094608) phosphodiesterase 1B, calmodulin-dependent
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PDE1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Monoclonal Anti-PDE1B, (C-terminal) antibody produced in mouse, clone 4F9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
Dipyridamole for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human