NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
Synonyms:
H2TF1, LYT-10, LYT10, NF-kB2, p105, p52
Species:
Human NFKB2 (4791), Mouse Nfkb2 (18034), Rat Nfkb2 (309452), Zebrafish nfkb2 (415100), chicken NFKB2 (386574), domestic cat NFKB2 (101080578), cow NFKB2 (526392), dog NFKB2 (486858), naked mole-rat Nfkb2 (101714147), domestic guinea pig Nfkb2 (100715820)
UniProtKB ID:
Gene ID:
- Human(4791) Summary: This gene encodes one of the subunits of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB transcription factor complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The NFkB complex can consist of different subunits that form both homo- or heterodimers which bind specific kappa-B elements in target genes. This gene encodes the p100 subunit that is processed into the active p52 subunit. This protein can function as both a transcriptional activator and repressor, depending on its dimer partner. Alternate splicing results in both coding and non-coding variants. [provided by RefSeq, May 2012]
- Mouse(18034) nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
- Rat(309452) nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100
- Zebrafish(415100) nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100
- chicken(386574) nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
- domestic cat(101080578) nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
- cow(526392) nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
- dog(486858) nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
- naked mole-rat(101714147) nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
- domestic guinea pig(100715820) nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-NF-κB2 Antibody, clone 4K3V3, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
western blot
Anti-phospho-NF-κB p100 (pSer872) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
western blot
ANTI-NFKB(P100) (C-TERM S866/870) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-phospho NFkB p52, (Ser222) Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-NF-κB p100 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Blocker
Product Number
Description
Species
Small Molecule - Inhibitor
Product Number
Description
Species
Proteins
Product Number
Description
Species
NFKB2 (1-454), GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human