LCK
lymphocyte-specific protein tyrosine kinase
Synonyms:
LSK, YT16, p56lck, pp58lck
Species:
Human LCK (3932), Mouse Lck (16818), Rat Lck (313050), sheep LCK (100216439), Domestic Rabbit LCK (100349102), domestic guinea pig Lck (100728811), naked mole-rat Lck (101714396), Zebrafish lck (414333), cow LCK (508890), Horse LCK (100146139) ...More
UniProtKB ID:
Gene ID:
- Human(3932) Summary: This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq, Jul 2008]
- Mouse(16818) lymphocyte protein tyrosine kinase
- Rat(313050) lymphocyte-specific protein tyrosine kinase
- sheep(100216439) lymphocyte-specific protein tyrosine kinase
- Domestic Rabbit(100349102) lymphocyte-specific protein tyrosine kinase
- domestic guinea pig(100728811) lymphocyte-specific protein tyrosine kinase
- naked mole-rat(101714396) lymphocyte-specific protein tyrosine kinase
- Zebrafish(414333) lymphocyte-specific protein tyrosine kinase
- cow(508890) lymphocyte-specific protein tyrosine kinase
- Horse(100146139) lymphocyte-specific protein tyrosine kinase
- domestic cat(101098805) lymphocyte-specific protein tyrosine kinase
- dog(478151) lymphocyte-specific protein tyrosine kinase
- chicken(396460) lymphocyte-specific protein tyrosine kinase
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ELISA
Product Number
Description
Species
Small Molecule - Antagonist
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-LCK antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, canine, human, mouse, pig, rat
Application
ELISA
western blot
western blot
ANTI-LCK antibody produced in mouse, clone 8B10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-Lck Antibody, clone 3A5, clone 3A5, Upstate®, from mouse,
Species Reactivity
human, mouse, rat
Application
immunoprecipitation (IP)
western blot
western blot
Monoclonal Anti-LCK antibody produced in mouse, clone LCK-01,
Species Reactivity
human
Application
flow cytometry
Anti-Phospho-Lck-Y505 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3‑d]pyrimidin-4-ylamine, ≥98% (HPLC),
Species
human
Proteins
Product Number
Description
Species
LCK, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human