Skip to Content
Merck

IKBKB

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta

Synonyms:
IKK-beta, IKK2, IKKB, NFKBIKB
Species:
UniProtKB ID:
Gene ID:
  • Human(3551) Summary: The protein encoded by this gene phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex, causing dissociation of the inhibitor and activation of NF-kappa-B. The encoded protein itself is found in a complex of proteins. Several transcript variants, some protein-coding and some not, have been found for this gene. [provided by RefSeq, Sep 2011]
  • Mouse(16150) inhibitor of kappaB kinase beta
  • Rat(84351) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
  • Zebrafish(563560) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
  • chicken(426792) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
  • cow(281854) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
  • domestic cat(100142682) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
  • dog(482839) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
  • domestic guinea pig(100724538) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
  • naked mole-rat(101711077) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-phospho-IKK-β (pTyr199) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-IKK beta antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunocytochemistry

immunofluorescence

western blot
Anti-IKK beta antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
ANTI-IKBKB antibody produced in mouse, clone 3C12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
Anti-IKBKB antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Norharmane, crystalline,
Species
human
CDDO Methyl Ester, ≥98% (HPLC),
Species
human

Proteins

Product Number
Description
Species
IKKβ, ,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Ikbkb,
Species
mouse
MISSION® esiRNA, targeting human IKBKB,
Species
human