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Merck

GDF5

growth differentiation factor 5

Synonyms:
BDA1C, BMP14, CDMP1, LAP4, OS5, SYM1B, SYNS2
Species:
UniProtKB ID:
Gene ID:
  • Human(8200) Summary: The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type; brachydactyly, type C; and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development. [provided by RefSeq, Jul 2008]
  • Mouse(14563) growth differentiation factor 5
  • Rat(252835) growth differentiation factor 5
  • Zebrafish(30195) growth differentiation factor 5
  • chicken(374249) growth differentiation factor 5
  • dog(485850) growth differentiation factor 5
  • Horse(100034228) growth differentiation factor 5
  • cow(539559) growth differentiation factor 5
  • domestic cat(101081533) growth differentiation factor 5
  • naked mole-rat(101696976) growth differentiation factor 5
  • domestic guinea pig(100723808) growth differentiation factor 5
  • sheep(101116499) growth differentiation factor 5
  • Domestic Rabbit(100328897) growth differentiation factor 5

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-GDF5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-GDF5OS antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

Proteins

Product Number
Description
Species
BMP-14 (GDF-5/CDMP-1) human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC),
Species
human
GDF-5 mouse, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC),
Species
mouse

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Gdf5,
Species
mouse
MISSION® esiRNA, targeting human GDF5,
Species
human