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Merck

CRKL

v-crk avian sarcoma virus CT10 oncogene homolog-like

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(1399) Summary: This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.[provided by RefSeq, Jan 2009]
  • Mouse(12929) v-crk sarcoma virus CT10 oncogene homolog (avian)-like
  • Rat(287942) v-crk avian sarcoma virus CT10 oncogene homolog-like
  • Zebrafish(556443) v-crk sarcoma virus CT10 oncogene homolog (avian)-like
  • dog(608125) v-crk sarcoma virus CT10 oncogene homolog (avian)-like
  • domestic cat(101084908) v-crk sarcoma virus CT10 oncogene homolog (avian)-like
  • cow(518180) v-crk sarcoma virus CT10 oncogene homolog (avian)-like
  • chicken(416939) v-crk sarcoma virus CT10 oncogene homolog-like
  • sheep(101117537) v-crk sarcoma virus CT10 oncogene homolog (avian)-like
  • naked mole-rat(101705695) v-crk sarcoma virus CT10 oncogene homolog (avian)-like
  • domestic guinea pig(100723968) v-crk sarcoma virus CT10 oncogene homolog (avian)-like

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CRKL antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-CRKL Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse, rat, rhesus macaque
Application
immunoprecipitation (IP)
western blot
Anti-CRKL antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-CRKL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-phospho-CrkL (Tyr207) Antibody, Upstate®, from rabbit,
Species Reactivity
human, mouse, rat
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CRKL,
Species
human
MISSION® esiRNA, targeting mouse Crkl,
Species
mouse