AIRE
autoimmune regulator
Synonyms:
AIRE1, APECED, APS1, APSI, PGA1
Species:
Human AIRE (326), Mouse Aire (11634), Rat Aire (294328), Zebrafish aire (100007662), cow AIRE (784775), domestic cat AIRE (101091039), dog AIRE (487796), chicken AIRE (429666), naked mole-rat Aire (101725873), domestic guinea pig Aire (100729880)
UniProtKB ID:
Gene ID:
- Human(326) Summary: This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012]
- Mouse(11634) autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)
- Rat(294328) autoimmune regulator
- Zebrafish(100007662) autoimmune regulator
- cow(784775) autoimmune regulator
- domestic cat(101091039) autoimmune regulator
- dog(487796) autoimmune regulator
- chicken(429666) autoimmune regulator
- naked mole-rat(101725873) autoimmune regulator
- domestic guinea pig(100729880) autoimmune regulator
- sheep(101102698) autoimmune regulator
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-AIRE antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-AIRE (Isoform 1) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, canine, human, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-AIRE (Isoforms 1 and 2) (AB2) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-AIRE (Isoforms 1 and 2) (AB1) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ChIP
ELISA
western blot
ELISA
western blot
Anti-AIRE Antibody, clone 5H12, clone 5H12, from rat,
Species Reactivity
mouse
Application
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot