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N-068

Supelco

(±)-Normetanephrine-D3 hydrochloride solution

100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C9H10D3NO3·HCl
CAS Number:
1085333-97-6
Molecular Weight:
222.68
EC Number:
200-659-6
MDL number:
MFCD17018958
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

100 μg/mL in methanol (as free base)

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing
clinical testing

format

single component solution

storage temp.

−70°C

SMILES string

OC(C([2H])([2H])N)([2H])C1=CC(OC)=C(O)C=C1.Cl

InChI

1S/C9H13NO3.ClH/c1-13-9-4-6(8(12)5-10)2-3-7(9)11;/h2-4,8,11-12H,5,10H2,1H3;1H/i5D2,8D;

InChI key

VKFPRGQZWKTEON-IJJJTAPTSA-N

Related Categories

General description

Normetanephrine, a metabolite of norepinephrine, is a marker for catecholamine-secreting tumors such as pheochromocytoma. This internal standard is suitable for LC-MS/MS monitoring of normetanephrine levels in urine or plasma for diagnostic testing or endocrinology.

Application


  • Reference standard for mass spectrometry: (±)-Normetanephrine-D₃ hydrochloride solution is widely used as a stable isotope-labeled standard in mass spectrometry for analyzing catecholamine metabolites. This application is essential for enhancing the accuracy of quantitative measurements in biomedical research (Zou et al., 2024).

  • Research tool in neurotransmitter metabolism: The solution serves as an invaluable research tool in the study of neurotransmitter metabolism, particularly in the context of understanding catecholamine pathways in neurological disorders. Its application helps delineate the biochemical processes involving catecholamines, aiding in the development of therapeutic strategies (Jaafar et al., 2024).

  • Analytical standard in biomedical research: As a deuterated form of normetanephrine, the hydrochloride solution is used extensively as an analytical standard in various biomedical assays, contributing significantly to the standardization and reproducibility of experimental results (Chen et al., 2024).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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C-111

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C-110

Catecholamine Mix 2 (Metanephrines) solution, 1.0 mg/mL each component in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

D-072

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D-081

Dopamine hydrochloride solution, 1.0 mg/mL in methanol with 5% 1 M HCl (as free base), ampule of 1 mL, certified reference material, Cerilliant®

E-077

(±)-Epinephrine-D6 solution, 100 μg/mL in methanol with 5% 1 M HCl, ampule of 1 mL, certified reference material, Cerilliant®

H-091

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H-092

4-Hydroxy-3-methoxyphenyl-D3-acetic-D2 Acid solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

M-148

(±)-Metanephrine-D3 hydrochloride solution, 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

N-069

(±)-Norepinephrine-D6 hydrochloride solution, 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

H-152

5-Hydroxyindole-2,4,6,7-d4-3-acetic-2,2-d2 acid (5-HIAA-D6) solution, 100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

N-152

(±)-Normetanephrine hydrochloride solution, 1 mg/mL in methanol ((as free base)), certified reference material, ampule of 1 mL, Cerilliant®

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup

Certificates of Analysis (COA)

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