901456

Amine poly(ethylene glycol)-block-poly(lactide-co-glycolide)

PEG average M_n 5000, PLGA average M_n 15000, lactide:glycolide 50:50

• Synonym(s): Amine-PEG-b-PLGA, Amine-PEG-PLGA
• Linear Formula: C₅H₁₂ONS(C₂H₄O)_n[(C₂H₂O₂)_x(C₃H₄O₂)_y]_m
• UNSPSC Code: 12352116
• NACRES: NA.23

Properties

• description: Feed Ratio: 50:50 +/-5 (Lactide:Glycolide, by NMR); Identity: Conforms to structure (by NMR)
• Quality Level: 100
• form: powder
• feed ratio: lactide:glycolide 50:50
• mol wt: PEG M_n 4000-6000 g/mol (by NMR); PEG average M_n 5000; PLGA M_n 13500-16500 g/mol (by NMR); PLGA average M_n 15000
• color: white
• shipped in: dry ice
• storage temp.: −20°C

Description

Application

Amine poly(ethylene glycol)-block-poly(lactide-co-glycolide) is an amine-functionalized, biocompatible, amphiphilic block copolymer. Due to its self-assembling properties, this material can be used in the formation of nanoparticles for drug delivery. Additionally, due to the amine-functionalization of the PEG block, this material can be used to rapidly covalently conjugate biomolecules, API, or targeting ligands. Potential uses include the targeted and/or controlled release of cancer drugs, anti-inflammatory drugs, antibiotics, or anaesthetic agents.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable