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Merck

WFDC1

WAP four-disulfide core domain 1

Synonyms:
PS20
Species:
UniProtKB ID:
Gene ID:
  • Human(58189) Summary: This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. The encoded protein shares 81% amino acid identity with the rat ps20 protein, which was originally identified as a secreted growth inhibitor. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. Owing to its location and a possible growth inhibitory property of its gene product, this gene is suggested to be a tumor suppressor gene. [provided by RefSeq, Jul 2008]
  • Mouse(67866) WAP four-disulfide core domain 1
  • Rat(171112) WAP four-disulfide core domain 1
  • cow(505366) WAP four-disulfide core domain 1
  • sheep(101102920) WAP four-disulfide core domain 1
  • domestic guinea pig(100727072) WAP four-disulfide core domain 1
  • naked mole-rat(101710653) WAP four-disulfide core domain 1
  • Zebrafish(560860) WAP four-disulfide core domain 1
  • domestic cat(101088637) WAP four-disulfide core domain 1
  • dog(489682) WAP four-disulfide core domain 1
  • chicken(395238) WAP four-disulfide core domain 1

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-WFDC1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-Wfdc1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
mouse, rat
Application
ELISA
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human WFDC1,
Species
human
MISSION® esiRNA, targeting mouse Wfdc1,
Species
mouse