LRP6
low density lipoprotein receptor-related protein 6
Synonyms:
ADCAD2
Species:
Human LRP6 (4040), Mouse Lrp6 (16974), Rat Lrp6 (312781), Zebrafish lrp6 (100003877), chicken LRP6 (419097), dog LRP6 (477692), domestic cat LRP6 (101082246), Horse LRP6 (100063409), cow LRP6 (536328), sheep LRP6 (101112971) ...More
UniProtKB ID:
Gene ID:
- Human(4040) Summary: This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009]
- Mouse(16974) low density lipoprotein receptor-related protein 6
- Rat(312781) low density lipoprotein receptor-related protein 6
- Zebrafish(100003877) low-density lipoprotein receptor-related protein 6
- chicken(419097) low density lipoprotein receptor-related protein 6
- dog(477692) low density lipoprotein receptor-related protein 6
- domestic cat(101082246) low density lipoprotein receptor-related protein 6
- Horse(100063409) low density lipoprotein receptor-related protein 6
- cow(536328) low density lipoprotein receptor-related protein 6
- sheep(101112971) low density lipoprotein receptor-related protein 6
- domestic guinea pig(100735282) low density lipoprotein receptor-related protein 6
- naked mole-rat(101703711) low density lipoprotein receptor-related protein 6
- Domestic Rabbit(100352000) low density lipoprotein receptor-related protein 6
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-LRP6 Antibody, clone 1C10, clone 1C10, from mouse,
Species Reactivity
human, mouse, rat
Application
immunoprecipitation (IP)
western blot
western blot
Anti-LRP6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-LRP6 (C-term H1497) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-LRP6 (center) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-phospho-LRP-6 (Thr1479), from rabbit,
Species Reactivity
human, mouse, rhesus monkey
Application
inhibition assay
western blot
western blot