GAD2
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
Synonyms:
GAD65
Species:
Human GAD2 (2572), Mouse Gad2 (14417), Rat Gad2 (24380), Zebrafish gad2 (550403), Thale Cress GAD2 (842908), chicken GAD2 (395395), domestic cat GAD2 (101082244), cow GAD2 (512459), dog GAD2 (487107), sheep GAD2 (101106448) ...More
UniProtKB ID:
Gene ID:
- Human(2572) Summary: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]
- Mouse(14417) glutamic acid decarboxylase 2
- Rat(24380) glutamate decarboxylase 2
- Zebrafish(550403) glutamate decarboxylase 2
- Thale Cress(842908) glutamate decarboxylase 2
- chicken(395395) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
- domestic cat(101082244) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
- cow(512459) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
- dog(487107) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
- sheep(101106448) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
- naked mole-rat(101698166) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
- domestic guinea pig(100734029) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-GAD2 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2736, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-GAD2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-Glutamate Decarboxylase Antibody, 65 kDa isoform, clone GAD-6, clone GAD-6, Chemicon®, from mouse,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
western blot
Anti-GAD65 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
canine, human, mouse, pig, porcine, rat
Application
western blot
Anti-GAD2/GAD65 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, chimpanzee, human, mouse, rat
Application
ELISA
western blot
western blot
Proteins
Product Number
Description
Species