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Merck

CASR

calcium-sensing receptor

Synonyms:
CAR, EIG8, FHH, FIH, GPRC2A, HHC, HHC1, HYPOC1, NSHPT, PCAR1
Species:
UniProtKB ID:
Gene ID:
  • Human(846) Summary: The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. [provided by RefSeq, Jul 2008]
  • Mouse(12374) calcium-sensing receptor
  • Rat(24247) calcium-sensing receptor
  • sheep(101112527) calcium-sensing receptor
  • naked mole-rat(101725174) calcium-sensing receptor
  • domestic guinea pig(100718111) calcium-sensing receptor
  • chicken(418266) calcium-sensing receptor
  • domestic cat(100302732) calcium-sensing receptor
  • Horse(100034084) calcium-sensing receptor
  • cow(281038) calcium-sensing receptor
  • dog(488007) calcium-sensing receptor

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-phospho-Calcium Sensing Receptor (pThr888) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

western blot
Anti-Ca++ Sensing Receptor Antibody, Chemicon®, from rabbit,
Species Reactivity
human
Application
ELISA
western blot
Anti-Calcium Sensing Receptor antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-CASR antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-CASR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CASR,
Species
human