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Merck

ASAH1

N-acylsphingosine amidohydrolase (acid ceramidase) 1

Synonyms:
AC, ACDase, ASAH, PHP, PHP32, SMAPME
Species:
UniProtKB ID:
Gene ID:
  • Human(427) Summary: This gene encodes a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally. The encoded protein catalyzes the synthesis and degradation of ceramide into sphingosine and fatty acid. Mutations in this gene have been associated with a lysosomal storage disorder known as Farber disease. Multiple transcript variants encoding several distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(11886) N-acylsphingosine amidohydrolase 1
  • Rat(84431) N-acylsphingosine amidohydrolase (acid ceramidase) 1
  • chicken(422727) N-acylsphingosine amidohydrolase (acid ceramidase) 1
  • cow(510620) N-acylsphingosine amidohydrolase (acid ceramidase) 1
  • domestic cat(101082231) N-acylsphingosine amidohydrolase (acid ceramidase) 1
  • dog(482897) N-acylsphingosine amidohydrolase (acid ceramidase) 1
  • naked mole-rat(101724913) N-acylsphingosine amidohydrolase (acid ceramidase) 1
  • domestic guinea pig(100735549) N-acylsphingosine amidohydrolase (acid ceramidase) 1
  • sheep(101117904) N-acylsphingosine amidohydrolase (acid ceramidase) 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-ASAH1 antibody produced in mouse, clone 2C9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry

western blot
Anti-ASAH1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-ASAH1, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rat
Application
western blot
Anti-ASAH1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-ASAH1 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ASAH1,
Species
human