AR
androgen receptor
Synonyms:
AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM
Species:
Human AR (367), Mouse Ar (11835), Rat Ar (24208), Zebrafish ar (100005148), chicken AR (422165), fruit fly ar (44503), domestic cat AR (101081787), cow AR (280675), Horse AR (100033980), domestic cat AR (751827) ...More
UniProtKB ID:
Gene ID:
- Human(367) Summary: The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
- Mouse(11835) androgen receptor
- Rat(24208) androgen receptor
- Zebrafish(100005148) androgen receptor
- chicken(422165) androgen receptor
- fruit fly(44503) abdomen rotatum
- domestic cat(101081787) androgen receptor
- cow(280675) androgen receptor
- Horse(100033980) androgen receptor
- domestic cat(751827) androgen receptor
- dog(403588) androgen receptor
- Goat(100860827) androgen receptor
- Domestic Rabbit(100009193) androgen receptor
- sheep(443042) androgen receptor
- domestic guinea pig(100726891) androgen receptor
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Small Molecule - Activator
Product Number
Description
Species
Small Molecule - Agonist
Product Number
Description
Species
17α-Methyltestosterone solution, 1.0 mg/mL in 1,2-dimethoxyethane, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Methandienone solution, 1.0 mg/mL in 1,2-dimethoxyethane, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Small Molecule - Antagonist
Product Number
Description
Species
Flutamide for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Androgen Receptor antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Androgen Receptor antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ChIP
ELISA
immunohistochemistry
western blot
ELISA
immunohistochemistry
western blot
Anti-AR antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
dog, horse, human, pig
Application
western blot
Anti-Androgen Receptor (C-term) antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP242, affinity isolated antibody,
Species Reactivity
dog, human, mouse, pig, rabbit, rat
Application
immunohistochemistry
Anti-phospho-Androgen Receptor (pTyr363) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
western blot
Small Molecule - Blocker
Product Number
Description
Species
Small Molecule - Inhibitor
Product Number
Description
Species
Small Molecule - Ligand
Product Number
Description
Species