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Merck

Rising serum thyroxine levels and chorea in graves' disease.

Pediatrics (2013-01-09)
Coralie Leblicq, Michel Duval, Lionel Carmant, Guy Van Vliet, Nathalie Alos
ABSTRACT

A 15-year-old girl presented with chorea as a first sign of Graves' hyperthyroidism. Chorea abated with antithyroid drug treatment and reappeared when hyperthyroidism recurred but not when thyrotropin receptor antibodies increased after administration of (131)I. Therefore, chorea in this patient is associated with hyperthyroxinemia and not with autoantibodies.

MATERIALS
Product Number
Brand
Product Description

Supelco
Methimazole, VETRANAL®, analytical standard
Supelco
Methimazole, analytical standard
Sigma-Aldrich
2-Mercapto-1-methylimidazole, ≥99%