80023449
TSKgel® UP-SW3000 (2 µm) HPLC Columns
L x I.D. 15 cm × 4.6 mm, diol phase
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product name
TSKgel® UP-SW3000 HPLC Column, phase diol, L × I.D. 15 cm × 4.6 mm, 2 μm particle size
material
stainless steel
Agency
suitable for USP L20
suitable for USP L59
product line
TSKgel®
manufacturer/tradename
Tosoh 0023449
parameter
≤0.5 M salt concentration
0-30% aqueous soluble organic solvents
0.35 mL/min flow rate
10-30 °C temp. range
340 bar pressure
technique(s)
HPLC: suitable
L × I.D.
15 cm × 4.6 mm
matrix
silica particle platform
matrix active group
diol phase
particle size
2 μm
pore size
250 Å
pH range
2.5-7.5
separation technique
size exclusion (SEC)
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Application
- Free payloads and related species from antibody drug conjugates (ADCs) and their aggregates, during their determination by using 1-dimensional (1D) gradient size exclusion chromatography (SEC).
- Protein biopharmaceuticals in aqueous solutions, during their analysis by SEC.
Other Notes
Legal Information
antibody
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Articles
Informative article on size exclusion chromatography columns for biomolecule separations. Using columns packed with sub-2 μm particles provides significant gains in efficiency over SEC columns packed with larger particles.
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