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Key Documents

232A-7

Sigma-Aldrich

Calretinin Rabbit Polyclonal Antibody

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.41

biological source

rabbit

conjugate

unconjugated

antibody form

Ig fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (232A-74)
vial of 0.5 mL concentrate (232A-75)
bottle of 1.0 mL predilute (232A-77)
vial of 1.0 mL concentrate (232A-76)
bottle of 7.0 mL predilute (232A-78)

manufacturer/tradename

Cell Marque™

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

control

mesothelioma

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic, nuclear

General description

Anti-calretinin has been shown to be useful in differentiating mesothelioma from adenocarcinomas from the lung and other sources.

Quality


IVD
IVD
IVD
RUO

Linkage

Calretinin Positive Control Slides, Product No. 232S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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M C Barberis et al.
Acta cytologica, 41(6), 1757-1761 (1997-12-09)
To document that a polyclonal antiserum to calretinin, a 29-kd calcium-binding protein, consistently decorates normal and tumor mesothelial cells in cytologic preparations. Thirty-three archival cytologic specimens from eight patients with histologically confirmed malignant mesothelioma and 13 from patients with metastatic
N G Ordóñez
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 11(10), 929-933 (1998-10-31)
Only recently have immunohistochemical markers been recognized that are commonly expressed in epithelial mesotheliomas but not in adenocarcinomas. Among these, calretinin generated a great deal of interest, but the number of studies evaluating the practical use of calretinin immunostaining in
M P Leers et al.
Histopathology, 32(3), 209-216 (1998-05-06)
To assess the diagnostic accuracy of combinations of antibodies in the differential diagnosis of metastatic carcinomas and mesotheliomas in pleural lesions. The specificity and sensitivity of the commercially available antibodies Ber-EP4, MOC-31, CEA, B72.3, CD15, E-cadherin and calretinin were evaluated
R L Attanoos et al.
Histopathology, 39(6), 584-588 (2002-03-21)
Malignant epithelioid mesothelioma shows marked cytoarchitectural diversity. The aim of the study was to evaluate how immunoreactivity with mesothelial markers related to histological pattern. Ninety-two cases of malignant epithelioid mesothelioma (60 pleural, 32 peritoneal) were examined and classified as exhibiting
Merce Jorda et al.
Applied immunohistochemistry & molecular morphology : AIMM, 10(1), 67-70 (2002-03-15)
Most adrenocortical neoplasms and pheochromocytomas can be diagnosed by a combination of clinical findings and morphologic features. Occasionally, however, this histologic differential diagnosis requires ancillary tests, such as immunohistochemistry. Both tumors are generally negative for epithelial markers but express synaptophysin.
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