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Merck

TNFRSF1B

tumor necrosis factor receptor superfamily, member 1B

Synonyms:
CD120b, TBPII, TNF-R-II, TNF-R75, TNFBR, TNFR1B, TNFR2, TNFR80, p75, p75TNFR
Species:
UniProtKB ID:
Gene ID:
  • Human(7133) Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008]
  • Mouse(21938) tumor necrosis factor receptor superfamily, member 1b
  • Rat(156767) tumor necrosis factor receptor superfamily, member 1b
  • cow(338033) tumor necrosis factor receptor superfamily, member 1B
  • sheep(100240715) tumor necrosis factor receptor superfamily, member 1B
  • domestic guinea pig(100723273) tumor necrosis factor receptor superfamily, member 1B
  • naked mole-rat(101712824) tumor necrosis factor receptor superfamily, member 1B
  • Zebrafish(100037357) tumor necrosis factor receptor superfamily, member 1B
  • chicken(395083) tumor necrosis factor receptor superfamily, member 1B
  • dog(487437) tumor necrosis factor receptor superfamily, member 1B
  • domestic cat(101080392) tumor necrosis factor receptor superfamily, member 1B

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ELISA

Product Number
Description
Species
Rhesus Macaque TNFR2 ELISA, for serum, plasma and cell culture supernatants,
Species
Human soluble TNF Receptor 2 ELISA Kit, for serum, plasma for serum, plasma, cell culture supernatant and urine,
Species
human
Mouse Tnfrsf1B / Tumor Necrosis Factor Receptor Superfamily Member 1B ELISA Kit, ,
Species
mouse

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Tumor Necrosis Factor Soluble Receptor Type II antibody produced in goat, IgG fraction of antiserum, lyophilized powder,
Species Reactivity
human
Application
immunocytochemistry
western blot
Anti-TNFRSF1B antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot
Anti-TNFRSF1B antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-TNF Receptor II, antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

western blot
Anti-TNFR2/TNFRSF1B Antibody, clone 7S1K0, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
western blot

Proteins

Product Number
Description
Species
sTNF-receptor Type II human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
human
Tumor Necrosis Factor Soluble Receptor II (TNF sRII)/Fc Chimera human, >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture,
Species
human
Tumor Necrosis Factor Soluble Receptor I (TNF sRI)/Fc Chimera human, >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human TNFRSF1B,
Species
human
MISSION® esiRNA, targeting mouse Tnfrsf1b,
Species
mouse