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Merck

KIFAP3

kinesin-associated protein 3

Synonyms:
FLA3, KAP-1, KAP-3, KAP3, SMAP, Smg-GDS, dJ190I16.1
Species:
UniProtKB ID:
Gene ID:
  • Human(22920) Summary: The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
  • Mouse(16579) kinesin-associated protein 3
  • Rat(289168) kinesin-associated protein 3
  • chicken(424395) kinesin-associated protein 3
  • cow(518402) kinesin-associated protein 3
  • Horse(100059088) kinesin-associated protein 3
  • domestic cat(101084337) kinesin-associated protein 3
  • dog(100685317) kinesin-associated protein 3
  • domestic guinea pig(100718672) kinesin-associated protein 3
  • naked mole-rat(101721676) kinesin-associated protein 3
  • sheep(101102827) kinesin-associated protein 3
  • Domestic Rabbit(100345771) kinesin-associated protein 3

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-KIFAP3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
Species Reactivity
human
Application
immunohistochemistry
Anti-KIFAP3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
Species Reactivity
human
Application
immunohistochemistry
Rabbit anti-Phospho KAP-1 (S824) Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Species Reactivity
human, mouse
Application
immunocytochemistry
immunofluorescence

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-KIFAP3 Antibody, clone 1S7J7, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunofluorescence
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human KIFAP3,
Species
human