HYAL2
hyaluronoglucosaminidase 2
Synonyms:
LUCA2
Species:
Human HYAL2 (8692), Mouse Hyal2 (15587), Rat Hyal2 (64468), Zebrafish hyal2 (559228), chicken HYAL2 (415908), domestic cat HYAL2 (101094000), dog HYAL2 (484760), Horse HYAL2 (100061845), cow HYAL2 (281838), domestic guinea pig Hyal2 (100716485) ...More
UniProtKB ID:
Gene ID:
- Human(8692) Summary: This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR.[provided by RefSeq, Mar 2010]
- Mouse(15587) hyaluronoglucosaminidase 2
- Rat(64468) hyaluronoglucosaminidase 2
- Zebrafish(559228) hyaluronoglucosaminidase 2
- chicken(415908) hyaluronoglucosaminidase 2
- domestic cat(101094000) hyaluronoglucosaminidase 2
- dog(484760) hyaluronoglucosaminidase 2
- Horse(100061845) hyaluronoglucosaminidase 2
- cow(281838) hyaluronoglucosaminidase 2
- domestic guinea pig(100716485) hyaluronoglucosaminidase 2
- naked mole-rat(101709759) hyaluronoglucosaminidase 2
- sheep(443154) hyaluronoglucosaminidase 2
- Domestic Rabbit(100009375) hyaluronoglucosaminidase 2
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-HYAL2 antibody produced in mouse, purified immunoglobulin,
Species Reactivity
human
Application
western blot
Anti-HYAL2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Proteins
Product Number
Description
Species
Hyaluronidase from bovine testes, Type IV-S, powder, suitable for mouse embryo cell culture, 750-3000 units/mg solid,
Species
cow
Hyaluronidase from bovine testes, Type IV-S, lyophilized powder (essentially salt-free), 750-3000 units/mg solid,
Species
cow
Hyaluronidase from bovine testes, Type VI-S, lyophilized powder, 3,000-15,000 units/mg solid,
Species
cow