- [N-dealkylation of chlorimipramine and chlorpromazine in patients undergoing chronic treatment with both drugs: preliminary results].
[N-dealkylation of chlorimipramine and chlorpromazine in patients undergoing chronic treatment with both drugs: preliminary results].
Bollettino della Societa italiana di biologia sperimentale (1984-09-30)
G P Sgaragli, R Ninci, L Della Corte, R Borghesi, M Nardini, N Battistini
PMID6525292
ABSTRACT
Data obtained in this preliminary study show that in patients chronically treated either with Chlorimipramine (n = 6) or with Chlorpromazine (n = 2), significant amounts of the corresponding Nor1- and Nor2-metabolites were detected in plasma. The role of these metabolites in the overall therapeutic effect is under investigation.
MATERIALS
Product Number
Brand
Product Description
Chlorpromazine impurity D, European Pharmacopoeia (EP) Reference Standard