SRP8021

NMNAT1 human

recombinant, expressed in E. coli, His tagged, >95% (SDS-PAGE)

• Synonym(s): EC 2.7.7.1, IL-1F9, NMN adenylyltransferase 1, Nicotinamide mononucleotide adenylyltransferase 1
• CAS Number: 2230771-74-9
• UNSPSC Code: 12352202
• NACRES: NA.32

Properties

• biological source: human
• recombinant: expressed in E. coli
• tag: His tagged
• Assay: >95% (SDS-PAGE)
• form: liquid
• mol wt: monomer ~33.3 kDa
• packaging: pkg of 10 μg
• concentration: ≥0.2 mg/mL
• color: clear
• UniProt accession no.: Q9HAN9
• shipped in: dry ice
• storage temp.: −20°C
• Gene Information: human ... NMNAT1(64802)

Description

General description

Nuclear NMNAT isoform. Catalyzes the formation of NAD⁺ from nicotinamide mononucleotide (NMN) and ATP. It can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. Interacts with PARP-1/ARTD1. Protects against axonal degeneration following mechanical or toxic insults. Widely expressed.

Physical form

Solution in 50 mM sodium phosphate, pH 8.0, containing 300 mM sodium chloride, 2 mM DTT and 10% glycerol.

Other Notes

Human full-length NMNAT1 (aa 1-279) is fused at the N-terminus to a His-tag.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable