PHR1788

Docosahexaenoic Acid Ethyl Ester

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(s): 4,7,10,13,16,19-Docosahexaenoic acid ethyl ester
• Empirical Formula (Hill Notation): C₂₄H₃₆O₂
• CAS Number: 81926-94-5
• Molecular Weight: 356.54
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• Agency: traceable to Ph. Eur. D2954600; traceable to USP 1224620
• API family: docosahexaenoic acid ethyl ester
• CofA: current certificate can be downloaded
• packaging: pkg of 1 g
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: -10 to -25°C
• InChI: 1S/C24H36O2/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24(25)26-4-2/h5-6,8-9,11-12,14-15,17-18,20-21H,3-4,7,10,13,16,19,22-23H2,1-2H3/b6-5+,9-8+,12-11+,15-14+,18-17+,21-20+
• InChI key: ITNKVODZACVXDS-YATCGRJWSA-N

Description

General description

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Docosahexaenoic Acid Ethyl Ester is the ethyl ester of docosahexaenoic acid, an essential omega-3 fatty acid.

Application

This pharmaceutical secondary standard can also be used as follows:

• Development and validation of a reverse phase high-performance liquid chromatography-tandem mass spectrometry (RP-HPLC-MS/MS)method to determine eicosapentaenoic acid and docosahexaenoic acid in their ethyl ester forms
• Simulated moving bed (SMB) chromatographic separation of ethyl esters of eicosapentaenoic acid and docosahexaenoic acids

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC1420 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

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Safety Information

• Storage Class Code: 10 - Combustible liquids
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable