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M-148

Supelco

(±)-Metanephrine-D3 hydrochloride solution

100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

Synonym(s):

(±)-Metanephrine-D3 HCl

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About This Item

Empirical Formula (Hill Notation):
C10H12D3NO3·HCl
CAS Number:
1215507-88-2
Molecular Weight:
236.71
EC Number:
200-659-6
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

100 μg/mL in methanol (as free base)

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing
clinical testing

format

single component solution

storage temp.

−70°C

General description

Measurement of metanephrine, a metabolite of epinephrine, is a useful tool in the diagnosis of diseases such as pheochromocytoma and adrenal medullary neoplasm. This internal standard is suitable for LC-MS/MS monitoring of metanephrine levels in plasma or urine for diagnostic testing, endocrinology, or clinical chemistry.

Application


  • High sensitivity catecholamine measurement: A study detailed the development of a high-sensitivity LC-MS/MS method for the measurement of 3-methoxytyramine, exploring its relationship with metanephrines and dopamine in plasma. This research underscores the utility of stable isotope-labeled compounds like (±)-Metanephrine-D₃ hydrochloride in biochemical assays related to catecholamine metabolism, offering significant insights for neurochemical analysis and drug development (Smy et al., 2021).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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