SCNN1A
sodium channel, non-voltage-gated 1 alpha subunit
Synonyms:
BESC2, ENaCa, ENaCalpha, SCNEA, SCNN1
Species:
Human SCNN1A (6337), Mouse Scnn1a (20276), Rat Scnn1a (25122), cow SCNN1A (282348), sheep SCNN1A (443488), naked mole-rat Scnn1a (101700410), domestic guinea pig Scnn1a (100135613), chicken SCNN1A (396050), domestic cat SCNN1A (101091122), dog SCNN1A (403650)
UniProtKB ID:
Gene ID:
- Human(6337) Summary: Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2009]
- Mouse(20276) sodium channel, nonvoltage-gated 1 alpha
- Rat(25122) sodium channel, nonvoltage-gated 1 alpha
- cow(282348) sodium channel, non-voltage-gated 1 alpha subunit
- sheep(443488) sodium channel, non-voltage-gated 1 alpha subunit
- naked mole-rat(101700410) sodium channel, non-voltage-gated 1 alpha subunit
- domestic guinea pig(100135613) sodium channel, nonvoltage-gated 1 alpha
- chicken(396050) sodium channel, non-voltage-gated 1 alpha subunit
- domestic cat(101091122) sodium channel, non-voltage-gated 1 alpha subunit
- dog(403650) sodium channel, non-voltage-gated 1 alpha subunit
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Small Molecule - Antagonist
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-ENaC alpha-PerCP antibody produced in mouse, clone 2G4,
Species Reactivity
mouse, rat
Application
immunohistochemistry
western blot
western blot
Monoclonal Anti-ENaC alpha-Allophycocyanin antibody produced in mouse, clone 2G4,
Species Reactivity
mouse, rat
Application
immunohistochemistry
western blot
western blot
Monoclonal Anti-ENaC alpha-Atto 390 antibody produced in mouse, clone 2G4,
Species Reactivity
mouse, rat
Application
immunohistochemistry
western blot
western blot
Monoclonal Anti-ENaC alpha-Allophycocyanin antibody produced in mouse, clone 14E10,
Species Reactivity
mouse, rat
Application
immunohistochemistry
western blot
western blot
Monoclonal Anti-ENaC alpha-Atto 390 antibody produced in mouse, clone 14E10,
Species Reactivity
mouse, rat
Application
immunohistochemistry
western blot
western blot
Small Molecule - Blocker
Product Number
Description
Species
Small Molecule - Inhibitor
Product Number
Description
Species