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Merck

RBFOX1

RNA binding protein, fox-1 homolog (C. elegans) 1

Synonyms:
2BP1, A2BP1, FOX-1, FOX1, HRNBP1
Species:
UniProtKB ID:
Gene ID:
  • Human(54715) Summary: The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
  • Mouse(268859) RNA binding protein, fox-1 homolog (C. elegans) 1
  • Rat(302920) RNA binding protein, fox-1 homolog (C. elegans) 1
  • Zebrafish(449554) RNA binding protein, fox-1 homolog (C. elegans) 1
  • Horse(100066233) RNA binding protein, fox-1 homolog (C. elegans) 1
  • domestic cat(101089565) RNA binding protein, fox-1 homolog (C. elegans) 1
  • dog(609116) RNA binding protein, fox-1 homolog (C. elegans) 1
  • chicken(416645) RNA binding protein, fox-1 homolog (C. elegans) 1
  • domestic guinea pig(100723769) RNA binding protein, fox-1 homolog (C. elegans) 1
  • naked mole-rat(101707083) RNA binding protein, fox-1 homolog (C. elegans) 1
  • cow(521304) RNA binding protein, fox-1 homolog (C. elegans) 1
  • sheep(101105300) RNA binding protein, fox-1 homolog (C. elegans) 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-RBFOX1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-RBFOX1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
Anti-Fox1 Antibody, clone A2BP1, clone A2BP1, from rat,
Species Reactivity
human, mouse
Application
immunocytochemistry
immunofluorescence

immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human RBFOX1,
Species
human