LATS2
large tumor suppressor kinase 2
Synonyms:
KPM
Species:
Human LATS2 (26524), Mouse Lats2 (50523), Rat Lats2 (305922), Zebrafish lats2 (567674), cow LATS2 (508208), Horse LATS2 (100050150), domestic cat LATS2 (101093824), dog LATS2 (477343), chicken LATS2 (418949), domestic guinea pig Lats2 (100725954) ...More
UniProtKB ID:
Gene ID:
- Human(26524) Summary: This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq, Jul 2008]
- Mouse(50523) large tumor suppressor 2
- Rat(305922) large tumor suppressor 2
- Zebrafish(567674) LATS, large tumor suppressor, homolog 2 (Drosophila)
- cow(508208) large tumor suppressor kinase 2
- Horse(100050150) LATS, large tumor suppressor, homolog 2 (Drosophila)
- domestic cat(101093824) LATS, large tumor suppressor, homolog 2 (Drosophila)
- dog(477343) LATS, large tumor suppressor, homolog 2 (Drosophila)
- chicken(418949) LATS, large tumor suppressor, homolog 2 (Drosophila)
- domestic guinea pig(100725954) large tumor suppressor kinase 2
- naked mole-rat(101705060) large tumor suppressor kinase 2
- sheep(101117941) LATS, large tumor suppressor, homolog 2 (Drosophila)
- Domestic Rabbit(100356876) LATS, large tumor suppressor, homolog 2 (Drosophila)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-LATS2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
immunofluorescence
immunohistochemistry
immunofluorescence
immunohistochemistry
Anti-LATS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-LATS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-phospho-LATS1/2 (pThr1079/1041) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
immunohistochemistry
Anti-phospho-LATS1-T1079/LATS2-T1041 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot
Proteins
Product Number
Description
Species
LATS2 (480-1088), GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
esiRNA
Product Number
Description
Species