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Merck

HIST3H3

histone cluster 3, H3

Synonyms:
H3.4, H3/g, H3FT, H3t
Species:
Human HIST3H3 (8290), Rat Hist3h3 (287352), dog HIST3H3 (480760)
UniProtKB ID:
Q16695, B2R5K3, Q6FGU4
Gene ID:
  • Human(8290) Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Jul 2008]
  • Rat(287352) histone cluster 3, H3
  • dog(480760) histone cluster 3, H3

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Antibodies

Product Number
Description
Species Reactivity
Application
ZRB1836
Anti-Histone H3-Lys9me2 Antibody, clone 2J13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, rat
Application
immunocytochemistry
immunohistochemistry
inhibition assay
western blot
ZRB1888
Anti-Histone H3-Lys9me3 Antibody, clone 4J8 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
affinity binding assay
immunohistochemistry
inhibition assay
western blot
SAB4200485
Anti-acetyl-Histone H3 (Ac-Lys27) antibody produced in rabbit, ~1.0 mg/mL, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
SAB4200353
Anti-acetyl-Histone H4 [Ac-Lys12] antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
SAB4300869
Anti-Histone H4R3me1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunoprecipitation (IP)
western blot

Proteins

Product Number
Description
Species
SRP0408
Histone Octamer full length human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Species
human