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  • Oxycodone + naloxone: choose morphine and optimal laxative therapy instead.

Oxycodone + naloxone: choose morphine and optimal laxative therapy instead.

Prescrire international (2013-02-02)
PMID23367675
ABSTRACT

At high doses of oxycodone, the fixed-dose combination of oxycodone plus naloxone complicates therapeutic management and will likely have lower analgesic efficacy.

MATERIALS
Product Number
Brand
Product Description
O1378
Supelco
Oxycodone hydrochloride, analytical standard
O-002
Supelco
Oxycodone solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®