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SMB00182

Sigma-Aldrich

Eudesmine

≥95% (LC/MS-ELSD)

Synonym(s):

Eudesamin, Eudesmin

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About This Item

Empirical Formula (Hill Notation):
C22H26O6
CAS Number:
526-06-7
Molecular Weight:
386.44
MDL number:
MFCD00274496
UNSPSC Code:
12352205
PubChem Substance ID:
329824848
NACRES:
NA.25

Assay

≥95% (LC/MS-ELSD)

form

powder

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

SMILES string

COc1ccc(cc1OC)[C@@H]2OCC3C2CO[C@H]3c4ccc(OC)c(OC)c4

InChI

1S/C22H26O6/c1-23-17-7-5-13(9-19(17)25-3)21-15-11-28-22(16(15)12-27-21)14-6-8-18(24-2)20(10-14)26-4/h5-10,15-16,21-22H,11-12H2,1-4H3/t15-,16-,21+,22+/m1/s1

InChI key

PEUUVVGQIVMSAW-DJDZNOHASA-N

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General description

Natural product derived from plant source.

Biochem/physiol Actions

Eudesmin is a component of a Brazilian folk medicine that has been used for blood pressure reduction. Eudesmin also is an inhibitor of TNF-alpha production and T cell proliferation.
Found in the Rutaceae family that has estrogenic and sedative effects.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Y G Chen et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 26(7), 477-479 (2003-06-05)
Isolate and identify the bioactive compounds from the root of Stellera chamejasma. The compounds were extracted with solvents, isolated by column chromatography and identified by spectroscopic methods. Seven compounds were isolated and identified as umbelliferone(1); daphnoretin (2); 2,6-dimethoxyl p-benzoquinone(3); (-)-eudesmin(4);
Suzanne Lim et al.
Planta medica, 73(15), 1563-1567 (2007-12-13)
The present study focuses on eudesmin (bicyclic lignan, 0.15 % of dry leaves) and diphyllin (arylnaphthalene lignan, 0.1 % of dry roots), both isolated from H. perforatum Kar. et Kir, a Rutaceae species endemic to Uzbekistan. We first compared their
Subhas Chandra Roy et al.
The Journal of organic chemistry, 67(10), 3242-3248 (2002-05-11)
Intramolecular radical cyclization of suitably substituted epoxy ethers 4a-g using bis(cyclopentadienyl)titanium(III) chloride as the radical source resulted in trisubstituted tetrahydrofurano lignans and 2,6-diaryl-3,7-dioxabicyclo[3.3.0]octane lignans depending on the reaction conditions. The titanium(III) species was prepared in situ from commercially available titanocene
Juliana Montani Raimundo et al.
European journal of pharmacology, 606(1-3), 150-154 (2009-04-21)
In Brazilian folk medicine, extracts from Piper species are used to reduce blood pressure. Previously, we demonstrated the vasodilatory activity of crude extracts from leaves of Piper truncatum explaining their possible use in the treatment of hypertension in traditional medicine.
Isabele R Nascimento et al.
Pest management science, 60(4), 413-416 (2004-05-04)
Acetone and ethanol extracts of the tubercula and several compounds isolated from Aristolochia pubescens (Willd) were bioassayed on velvetbean caterpillars, Anticarsia gemmatalis (Hübner), for evaluation of the insecticidal activities. Of the extracts subjected to bioassay, the acetone extract showed the
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