MAB1962
Anti-Integrin β2 Antibody, clone P4H9
clone P4H9, Chemicon®, from mouse
Synonym(s):
CD18
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
Recommended Products
biological source
mouse
Quality Level
antibody form
purified antibody
antibody product type
primary antibodies
clone
P4H9, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
isotype
IgG3
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... ITGB2(3689)
Specificity
beta2 integrin on hematopoeitic cells. Not present on platelets, endothelial cells, epithelial cells or fibroblasts.
Application
Detect Integrin β2 using this Anti-Integrin β2 Antibody, clone P4H9 validated for use in IH.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Integrins
Integrins
Suitable for use in immunofluorescence at 1:1000.
Also suitable for aggregation inhibition assays using hematopoeitic cells or EBV-transformed B lymphocytes.
For extensive dilution, protein-containing or other stabilizing medium should be used. Final working dilutions must be determined by end user.
Also suitable for aggregation inhibition assays using hematopoeitic cells or EBV-transformed B lymphocytes.
For extensive dilution, protein-containing or other stabilizing medium should be used. Final working dilutions must be determined by end user.
Physical form
Format: Purified
Non-sterile buffer of 0.02M phosphate, 0.25M Sodium Chloride, pH 7.6,
0.1% sodium azide.
0.1% sodium azide.
Storage and Stability
Maintain between 2 and 8°C.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Find documentation for the products that you have recently purchased in the Document Library.
Transcriptional regulation of the interleukin-1beta promoter via fibrinogen engagement of the CD18 integrin receptor.
R L Perez, J D Ritzenthaler, J Roman
American Journal of Respiratory Cell and Molecular Biology null
L M Pierini et al.
Blood, 95(8), 2471-2480 (2001-02-07)
During cell migration, integrin attachments to the substratum provide the means to generate the traction and force necessary to achieve locomotion. Once the cell has moved over these attachments, however, it is equally important that integrins detach from the substratum.
J Roman et al.
Immunology, 98(2), 228-237 (1999-12-14)
Extracellular matrices (ECMs) can stimulate human monocytic cells to express interleukin-1beta (IL-1beta), a proinflammatory cytokine implicated in the regulation of tissue inflammation. In this study, we explored the intracellular mechanisms responsible for ECM induction of IL-1beta using human promonocytic U937
Andes virus recognition of human and Syrian hamster beta3 integrins is determined by an L33P substitution in the PSI domain.
Valery S Matthys,Elena E Gorbunova,Irina N Gavrilovskaya,Erich R Mackow
Journal of virology null
Alveolar type II cells from ethanol-fed rats produce a fibronectin-enriched extracellular matrix that promotes monocyte activation.
Lou Ann S Brown, Jeffrey D Ritzenthaler, David M Guidot, Jesse Roman
Alcohol null
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