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D214752

Sigma-Aldrich

Dipropylamine

99%

Synonym(s):

Di-n-propylamine, Dipropanamine, Dipropylamine (8CI), N,N-Di(n-propyl)amine, N,N-Dipropylamine, N-Propyl-1-propanamine, n-Dipropylamine

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About This Item

Linear Formula:
(CH3CH2CH2)2NH
CAS Number:
Molecular Weight:
101.19
Beilstein:
505974
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

99%

form

liquid

refractive index

n20/D 1.4049 (lit.)

bp

105-110 °C (lit.)

density

0.738 g/mL at 25 °C (lit.)

SMILES string

CCCNCCC

InChI

1S/C6H15N/c1-3-5-7-6-4-2/h7H,3-6H2,1-2H3

InChI key

WEHWNAOGRSTTBQ-UHFFFAOYSA-N

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General description

Dipropylamine is an aliphatic amine, commonly used as a deprotection reagent for fluorenylmethyloxycarbonyl (Fmoc) groups. Its nucleophilic properties, due to the lone pair of electrons on the nitrogen atom, allow it to effectively participate in nucleophilic substitution reactions.

Application

  • Separation of hydrocarbons: Nitrogen-containing switchable solvents, including dipropylamine, are used for the separation of hydrocarbons and their derivatives, showcasing the compound′s versatility in solvent applications (Liu et al., 2020).
  • Microextraction techniques: Dipropylamine-based dispersive micro-solid phase extraction combined with switchable hydrophilicity solvent is employed for enriching non-steroidal anti-inflammatory drugs from environmental water samples, demonstrating its utility in complex sample preparation (Di et al., 2020).
  • Homogeneous liquid-liquid microextraction: A new pH assisted homogeneous liquid-liquid microextraction method utilizing dipropylamine as a solvent with switchable hydrophilicity was developed for the GC-MS determination of methamphetamine, highlighting its effectiveness in analytical chemistry applications (Shahvandi et al., 2018).
  • Removal of contaminants: Research demonstrated the use of zeolite and powdered activated carbon in conjunction with dipropylamine for the simultaneous removal of ammonia and N-nitrosamine precursors from high ammonia water, underscoring its environmental application (Xue et al., 2018).
  • Nanosized synthesis: Dipropylamine was used in a co-templating synthesis approach for the production of high-yield nanosized (Si)AlPO-41 using ethanol polarity equalization, illustrating its role in materials science (Majano et al., 2015).

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1A - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

44.6 °F - closed cup

Flash Point(C)

7 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Siamak Kiani Shahvandi et al.
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In this study, a new method based on homogeneous liquid-phase microextraction was developed for the determination of methamphetamine (MA) in urine samples. Dipropylamine (DPA), as a solvent with switchable hydrophilicity, was used as the extraction solvent and can be miscible/immiscible
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