TXNRD3
thioredoxin reductase 3
Synonyms:
TGR, TR2, TRXR3
Species:
Human TXNRD3 (114112), Mouse Txnrd3 (232223), Rat Txnrd3 (297437), Zebrafish txnrd3 (352925), Horse TXNRD3 (100060514), domestic cat TXNRD3 (101090928), dog TXNRD3 (484619), chicken TXNRD3 (416031), cow TXNRD3 (319097), sheep TXNRD3 (101117116) ...More
UniProtKB ID:
Gene ID:
- Human(114112) Summary: This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein catalyzes the reduction of thioredoxin, and is implicated in the defense against oxidative stress. It contains a selenocysteine (Sec) residue (which is essential for catalytic activity), encoded by a UGA codon, at the penultimate C-terminal position. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
- Mouse(232223) thioredoxin reductase 3
- Rat(297437) thioredoxin reductase 3
- Zebrafish(352925) thioredoxin reductase 3
- Horse(100060514) thioredoxin reductase 3
- domestic cat(101090928) thioredoxin reductase 3
- dog(484619) thioredoxin reductase 3
- chicken(416031) thioredoxin reductase 3
- cow(319097) thioredoxin reductase 3
- sheep(101117116) thioredoxin reductase 3
- Domestic Rabbit(100358257) thioredoxin reductase 3
- domestic guinea pig(100719286) thioredoxin reductase 3
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