TRADD
TNFRSF1A-associated via death domain
Synonyms:
Hs.89862
Species:
Human TRADD (8717), Mouse Tradd (71609), Rat Tradd (246756), Zebrafish tradd (58130), chicken TRADD (415700), dog TRADD (611262), domestic cat TRADD (101097773), cow TRADD (504707), sheep TRADD (101111042), domestic guinea pig Tradd (100732953)
UniProtKB ID:
Gene ID:
- Human(8717) Summary: The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq, Jul 2008]
- Mouse(71609) TNFRSF1A-associated via death domain
- Rat(246756) TNFRSF1A-associated via death domain
- Zebrafish(58130) tnfrsf1a-associated via death domain
- chicken(415700) TNFRSF1A-associated via death domain
- dog(611262) TNFRSF1A-associated via death domain
- domestic cat(101097773) TNFRSF1A-associated via death domain
- cow(504707) TNFRSF1A-associated via death domain
- sheep(101111042) TNFRSF1A-associated via death domain
- domestic guinea pig(100732953) TNFRSF1A-associated via death domain
- naked mole-rat(101721567) TNFRSF1A-associated via death domain
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