Skip to Content
Merck

TIMP2

TIMP metallopeptidase inhibitor 2

Synonyms:
CSC-21K, DDC8
Species:
Human TIMP2 (7077), Mouse Timp2 (21858), Rat Timp2 (29543), chicken TIMP2 (374178), dog TIMP2 (403633), Horse TIMP2 (100034134), domestic cat TIMP2 (101083125), domestic guinea pig Timp2 (100135629), naked mole-rat Timp2 (101707659), Domestic Rabbit TIMP2 (100008689) ...More
UniProtKB ID:
P16035, Q16121, Q93006, Q9UDF7
Gene ID:
  • Human(7077) Summary: This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq, Jul 2008]
  • Mouse(21858) tissue inhibitor of metalloproteinase 2
  • Rat(29543) TIMP metallopeptidase inhibitor 2
  • chicken(374178) TIMP metallopeptidase inhibitor 2
  • dog(403633) TIMP metallopeptidase inhibitor 2
  • Horse(100034134) TIMP metallopeptidase inhibitor 2
  • domestic cat(101083125) TIMP metallopeptidase inhibitor 2
  • domestic guinea pig(100135629) tissue inhibitor of metalloproteinase 2
  • naked mole-rat(101707659) TIMP metallopeptidase inhibitor 2
  • Domestic Rabbit(100008689) TIMP metallopeptidase inhibitor 2
  • cow(282093) TIMP metallopeptidase inhibitor 2
  • sheep(100217406) TIMP metallopeptidase inhibitor 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Product Number
Description
Species
RAB1156
Rat TIMP-2 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
rat
RAB0579
Canine TIMP2 / Metalloproteinase Inhibitor 2 ELISA Kit, ,
Species
dog
RAB0472
Human TIMP-2 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human
RAB0473
Mouse TIMP-2 ELISA Kit, for serum, plasma and cell culture supernatant,
Species
mouse
RAB0879
Porcine TIMP2 / Tissue Inhibitor of Metalloproteinase-2 ELISA Kit, ,
Species

Antibodies

Product Number
Description
Species Reactivity
Application
SAB4502972
Anti-TIMP2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
western blot
MAB13446
Anti-TIMP-2 Antibody, clone 2TMP05, clone 2TMP05, Chemicon®, from mouse,
Species Reactivity
bovine, guinea pig, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
SAB5700746
Anti-TIMP2 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
western blot
SAB4200814
Anti-TIMP2 antibody, Mouse monoclonal, clone TM8, purified from hybridoma cell culture,
Species Reactivity
human
Application
immunofluorescence
western blot
MAB3310
Anti-TIMP-2 Antibody, clone 67-4H11, clone 67-4H11, Chemicon®, from mouse,
Species Reactivity
bovine, goat, guinea pig, human, mouse, rabbit, rat
Application
ELISA
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
SRP3174
TIMP-2 human, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Species
human