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Merck

SYN1

synapsin I

Synonyms:
SYN1a, SYN1b, SYNI
Species:
UniProtKB ID:
Gene ID:
  • Human(6853) Summary: This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(20964) synapsin I
  • Rat(24949) synapsin I
  • fruit fly(40424) Syntrophin-like 1
  • Zebrafish(570672) synapsin I
  • dog(491858) synapsin I
  • domestic cat(101094242) synapsin I
  • dog(100685486) synapsin I
  • Thale Cress(830432) RAD21-like protein SYN1
  • cow(281510) synapsin I
  • sheep(101114245) synapsin I
  • domestic guinea pig(100727353) synapsin I
  • naked mole-rat(101722592) synapsin I

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-phospho-Synapsin I (Ser62,Ser67) Antibody, Chemicon®, from rabbit,
Species Reactivity
rat
Application
western blot
Anti-SYN1 (Ab-9) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
western blot
ANTI-SYN1 antibody produced in mouse, clone 3E3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-Synapsin I Antibody, phosphoSer 603, Chemicon®, from rabbit,
Species Reactivity
rat
Application
western blot
Anti-Synapsin I Antibody, serum, Chemicon®,
Species Reactivity
bovine, human, mouse, rat
Application
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

western blot