STON1
stonin 1
SALF, SBLF, STN1, STNB1
Human STON1 (11037), Mouse Ston1 (77057), Rat Ston1 (360202), Zebrafish ston1 (100334703), Horse STON1 (100534008), dog STON1 (100534006), chicken STON1 (100534590), cow STON1 (100140704), Domestic Rabbit STON1 (100534010)
- Human(11037) Summary: Endocytosis of cell surface proteins is mediated by a complex molecular machinery that assembles on the inner surface of the plasma membrane. This gene encodes one of two human homologs of the Drosophila melanogaster stoned B protein. This protein is related to components of the endocytic machinery and exhibits a modular structure consisting of an N-terminal proline-rich domain, a central region of homology specific to the human stoned B-like proteins, and a C-terminal region homologous to the mu subunits of adaptor protein (AP) complexes. Read-through transcription of this gene into the neighboring downstream gene, which encodes TFIIA-alpha/beta-like factor, generates a transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010]
- Mouse(77057) stonin 1
- Rat(360202) stonin 1
- Zebrafish(100334703) stonin 1
- Horse(100534008) stonin 1
- dog(100534006) stonin 1
- chicken(100534590) stonin 1
- cow(100140704) stonin 1
- Domestic Rabbit(100534010) stonin 1
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