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Merck

STAT1

signal transducer and activator of transcription 1, 91kDa

Synonyms:
CANDF7, ISGF-3, STAT91
Species:
UniProtKB ID:
Gene ID:
  • Human(6772) Summary: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
  • Mouse(20846) signal transducer and activator of transcription 1
  • Rat(25124) signal transducer and activator of transcription 1
  • chicken(424044) signal transducer and activator of transcription 1, 91kDa
  • dog(488449) signal transducer and activator of transcription 1, 91kDa
  • cow(510814) signal transducer and activator of transcription 1, 91kDa
  • sheep(100307049) signal transducer and activator of transcription 1, 91kDa
  • Domestic Rabbit(100343893) signal transducer and activator of transcription 1, 91kDa
  • naked mole-rat(101718902) signal transducer and activator of transcription 1, 91kDa
  • domestic guinea pig(100724708) signal transducer and activator of transcription 1, 91kDa

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ELISA

Product Number
Description
Species
Phosphotyrosine STAT1 ELISA Kit, ,
Species
human
Phospho-Stat1 (pSer727) ELISA Kit, for detection of phospho-stat1 (pSer727) in human or mouse cell and tissue lysates,
Species
mouse, human
Phospho-Stat1 (pSer727) and pan-Stat1 ELISA Kit, for detection of phospho-stat1 (pSer727) and pan-stat1 in human or mouse cell and tissue lysates,
Species
mouse, human
Phospho-Stat1 (pTyr701) and pan-Stat1 ELISA Kit, for detection of phospho-stat1 (pTyr701) and pan-stat1 in human or mouse cell and tissue lysates,
Species
mouse, human
Phospho-Stat1 (pTyr701) ELISA Kit, for detection of phospho-stat1 (pTyr701) and pan-stat1 in human or mouse cell and tissue lysates,
Species
mouse, human

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-STAT1 (PhosphoSer727) antibody produced in mouse, clone PSM1,
Species Reactivity
human
Application
western blot
Anti-STAT1 (AB2) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, horse, human, pig, sheep
Application
western blot
Anti-phospho-STAT1 (pTyr701) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
Anti-STAT1α antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-phospho-STAT1 (pSer727) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
immunofluorescence
immunohistochemistry

western blot

Proteins

Product Number
Description
Species
STAT1 human, recombinant, expressed in insect cells, ≥70% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human STAT1,
Species
human
MISSION® esiRNA, targeting mouse Stat1,
Species
mouse