Skip to Content
Merck

SERPINA1

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1

Synonyms:
A1A, A1AT, AAT, PI, PI1, PRO2275, alpha1AT
Species:
Human SERPINA1 (5265), Rat Serpina1 (24648), Zebrafish serpina1 (322701), domestic cat SERPINA1 (101080897), dog SERPINA1 (480422), chicken SERPINA1 (423434), cow SERPINA1 (280699), sheep SERPINA1 (443388)
UniProtKB ID:
P01009, A6PX14, B2RDQ8, Q0PVP5, Q13672, Q53XB8, Q5U0M1, Q7M4R2
Gene ID:
  • Human(5265) Summary: The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Rat(24648) serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
  • Zebrafish(322701) serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
  • domestic cat(101080897) serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
  • dog(480422) serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
  • chicken(423434) serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
  • cow(280699) serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
  • sheep(443388) serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Product Number
Description
Species
RAB1079
Human Serpin A1 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
SAB2109236
Anti-SERPINA1 (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot
A0409
Anti-α1-Antitrypsin antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
human
Application
ELISA
immunoelectrophoresis
SAB4200198
Anti-Alpha-1-Antitrypsin (AAT) antibody,Mouse monoclonal, clone 1C2, purified from hybridoma cell culture,
Species Reactivity
human
Application
western blot

Proteins

Product Number
Description
Species
A9024
α1-Antitrypsin from human plasma, salt-free, lyophilized powder,
Species
human
A6150
α1-Antitrypsin from human plasma, salt-free, lyophilized powder,
Species
human

esiRNA

Product Number
Description
Species
EHU090971
MISSION® esiRNA, targeting human SERPINA1,
Species
human