PTPRN2
protein tyrosine phosphatase, receptor type, N polypeptide 2
Synonyms:
IA-2beta, IAR, ICAAR, PTPRP, R-PTP-N2
Species:
Human PTPRN2 (5799), Mouse Ptprn2 (19276), Rat Ptprn2 (29714), domestic guinea pig Ptprn2 (100723726), naked mole-rat Ptprn2 (101716326), Domestic Rabbit PTPRN2 (100340246), cow PTPRN2 (616515), Zebrafish ptprn2 (325033), Horse PTPRN2 (100067294), dog PTPRN2 (482825) ...More
UniProtKB ID:
Gene ID:
- Human(5799) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]
- Mouse(19276) protein tyrosine phosphatase, receptor type, N polypeptide 2
- Rat(29714) protein tyrosine phosphatase, receptor type, N polypeptide 2
- domestic guinea pig(100723726) protein tyrosine phosphatase, receptor type, N polypeptide 2
- naked mole-rat(101716326) protein tyrosine phosphatase, receptor type, N polypeptide 2
- Domestic Rabbit(100340246) protein tyrosine phosphatase, receptor type, N polypeptide 2
- cow(616515) protein tyrosine phosphatase, receptor type, N polypeptide 2
- Zebrafish(325033) protein tyrosine phosphatase, receptor type, N polypeptide 2
- Horse(100067294) protein tyrosine phosphatase, receptor type, N polypeptide 2
- dog(482825) protein tyrosine phosphatase, receptor type, N polypeptide 2
- domestic cat(101089683) protein tyrosine phosphatase, receptor type, N polypeptide 2
- chicken(420449) protein tyrosine phosphatase, receptor type, N polypeptide 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PTPRN2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot