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Merck

PLA2G1B

phospholipase A2, group IB (pancreas)

Synonyms:
PLA2, PLA2A, PPLA2
Species:
UniProtKB ID:
Gene ID:
  • Human(5319) Summary: Phospholipase A2 (EC 3.1.1.4) catalyzes the release of fatty acids from glycero-3-phosphocholines. The best known varieties are the digestive enzymes secreted as zymogens by the pancreas of mammals. Sequences of pancreatic PLA2 enzymes from a variety of mammals have been reported. One striking feature of these enzymes is their close homology to venom phospholipases of snakes. Other forms of PLA2 have been isolated from brain, liver, lung, spleen, intestine, macrophages, leukocytes, erythrocytes, inflammatory exudates, chondrocytes, and platelets (Seilhamer et al., 1986 [PubMed 3028739]
  • Mouse(18778) phospholipase A2, group IB, pancreas
  • Rat(29526) phospholipase A2, group IB, pancreas
  • cow(282457) phospholipase A2, group IB (pancreas)
  • sheep(101117700) phospholipase A2, group IB (pancreas)
  • domestic guinea pig(100732984) phospholipase A2, group IB (pancreas)
  • naked mole-rat(101699902) phospholipase A2, group IB (pancreas)
  • Zebrafish(571738) phospholipase A2, group IB (pancreas)
  • chicken(770292) phospholipase A2, group IB (pancreas)
  • chicken(416980) phospholipase A2, group IB (pancreas)
  • domestic cat(101095522) phospholipase A2, group IB (pancreas)
  • dog(404011) phospholipase A2, group IB (pancreas)

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Small Molecule - Inhibitor

Product Number
Description
Species
Arachidonyl trifluoromethyl ketone, oil, ≥97% (NMR),
Species
human
Indomethacin, 98.5-100.5% (in accordance with EP),
Species
human, mouse, rat
Indomethacin, meets USP testing specifications,
Species
human, mouse, rat
α-Sexithiophene, ,
Species
human, rat

Proteins

Product Number
Description
Species
Phospholipase A2 from bovine pancreas, lyophilized powder, ≥20 units/mg protein,
Species
cow
Phospholipase A2 from porcine pancreas, ammonium sulfate suspension, ≥600 units/mg protein,
Species