PC
pyruvate carboxylase
Synonyms:
PCB
Species:
Human PC (5091), Mouse pc (18517), Rat Pc (25104), fruit fly Pc (40358), cow PC (102030714), cow PC (102030715), cow PC (102030716), cow PC (102030897), cow PC (102030982), cow PC (102031061) ...More
UniProtKB ID:
Gene ID:
- Human(5091) Summary: This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(18517) phocomelic
- Rat(25104) pyruvate carboxylase
- fruit fly(40358) Polycomb
- cow(102030714) Milk protein content
- cow(102030715) Milk protein content
- cow(102030716) Milk protein content
- cow(102030897) Milk protein content
- cow(102030982) Milk protein content
- cow(102031061) Milk protein content
- cow(102030942) Milk protein content
- cow(338471) pyruvate carboxylase
- cow(100531427) Milk protein content
- Horse(100052853) pyruvate carboxylase
- domestic cat(101089547) pyruvate carboxylase
- dog(483704) pyruvate carboxylase
- chicken(374263) pyruvate carboxylase
- Zebrafish(58068) pyruvate carboxylase
- naked mole-rat(101711800) pyruvate carboxylase
- domestic guinea pig(100719498) pyruvate carboxylase
- Goat(100861129) pyruvate carboxylase
- sheep(101107484) pyruvate carboxylase
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PC antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Pyruvate Carboxylase antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, canine, human, mouse, pig, rat
Application
ELISA
western blot
western blot