NCOR2
nuclear receptor corepressor 2
Synonyms:
CTG26, N-CoR2, SMAP270, SMRT, SMRTE, SMRTE-tau, TNRC14, TRAC, TRAC-1, TRAC1
Species:
Human NCOR2 (9612), Mouse Ncor2 (20602), Rat Ncor2 (360801), Zebrafish ncor2 (561503), chicken NCOR2 (416815), cow NCOR2 (538549), Horse NCOR2 (100059253), domestic cat NCOR2 (101083973), dog NCOR2 (486242), domestic guinea pig Ncor2 (100720194) ...More
UniProtKB ID:
Gene ID:
- Human(9612) Summary: This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Apr 2011]
- Mouse(20602) nuclear receptor co-repressor 2
- Rat(360801) nuclear receptor co-repressor 2
- Zebrafish(561503) nuclear receptor co-repressor 2
- chicken(416815) nuclear receptor corepressor 2
- cow(538549) nuclear receptor corepressor 2
- Horse(100059253) nuclear receptor corepressor 2
- domestic cat(101083973) nuclear receptor corepressor 2
- dog(486242) nuclear receptor corepressor 2
- domestic guinea pig(100720194) nuclear receptor corepressor 2
- naked mole-rat(101702626) nuclear receptor corepressor 2
- sheep(101121042) nuclear receptor corepressor 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SMRTe Antibody, Upstate®, from rabbit,
Species Reactivity
human
Application
ChIP
immunocytochemistry
western blot
immunocytochemistry
western blot
Anti-SMRT Antibody, clone 1SM-1E7, ascites fluid, clone 1SM-1E7, from mouse,
Species Reactivity
human, mouse, rat
Application
western blot
ChIPAb+ SMRT - ChIP Validated Antibody and Primer Set, ascites fluid, from mouse,
Species Reactivity
human, mouse, rat
Application
ChIP
electrophoretic mobility shift assay
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
electrophoretic mobility shift assay
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot