NBL1
neuroblastoma 1, DAN family BMP antagonist
Synonyms:
D1S1733E, DAN, DAND1, NB, NO3
Species:
Human NBL1 (4681), Mouse Nbl1 (17965), Rat Nbl1 (50594), Zebrafish nbl1 (404629), cow NBL1 (535280), Horse NBL1 (100071893), dog NBL1 (487403), domestic cat NBL1 (101090533), chicken NBL1 (373952), sheep NBL1 (101108197) ...More
UniProtKB ID:
Gene ID:
- Human(4681) Summary: This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development. Alternatively spliced transcript variants have been identified for this gene. Read-through transcripts between this locus and the upstream mitochondrial inner membrane organizing system 1 gene (GeneID 440574) have been observed. [provided by RefSeq, May 2013]
- Mouse(17965) neuroblastoma, suppression of tumorigenicity 1
- Rat(50594) neuroblastoma 1, DAN family BMP antagonist
- Zebrafish(404629) neuroblastoma, suppression of tumorigenicity 1
- cow(535280) neuroblastoma 1, DAN family BMP antagonist
- Horse(100071893) neuroblastoma, suppression of tumorigenicity 1
- dog(487403) neuroblastoma, suppression of tumorigenicity 1
- domestic cat(101090533) neuroblastoma, suppression of tumorigenicity 1
- chicken(373952) neuroblastoma, suppression of tumorigenicity 1
- sheep(101108197) neuroblastoma, suppression of tumorigenicity 1
- domestic guinea pig(100732484) neuroblastoma 1, DAN family BMP antagonist
- naked mole-rat(101708204) neuroblastoma 1, DAN family BMP antagonist
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