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Merck

LOXL3

lysyl oxidase-like 3

Synonyms:
LOXL
Species:
UniProtKB ID:
Gene ID:
  • Human(84695) Summary: This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Alternatively spliced transcript variants of this gene have been reported but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(16950) lysyl oxidase-like 3
  • Rat(312478) lysyl oxidase-like 3
  • Zebrafish(553538) LOXL3 protein
  • domestic cat(101087470) lysyl oxidase-like 3
  • cow(613599) lysyl oxidase-like 3
  • Horse(100053584) lysyl oxidase-like 3
  • dog(483101) lysyl oxidase-like 3
  • chicken(425986) lysyl oxidase-like 3
  • sheep(101119969) lysyl oxidase-like 3
  • domestic guinea pig(100733784) lysyl oxidase-like 3
  • naked mole-rat(101726484) lysyl oxidase-like 3

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-LOXL3, affinity isolated antibody,
Species Reactivity
human, mouse
Application
immunohistochemistry