INHBB
inhibin, beta B
Human INHBB (3625), Mouse Inhbb (16324), Rat Inhbb (25196), Zebrafish inhbb (30275), chicken INHBB (396126), cow INHBB (530430), domestic cat INHBB (493742), domestic cat INHBB (101084643), domestic guinea pig Inhbb (100719829), Goat INHBB (100861250)
- Human(3625) Summary: The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. [provided by RefSeq, Jul 2008]
- Mouse(16324) inhibin beta-B
- Rat(25196) inhibin beta-B
- Zebrafish(30275) inhibin, beta B
- chicken(396126) inhibin, beta B
- cow(530430) inhibin, beta B
- domestic cat(493742) inhibin, beta B
- domestic cat(101084643) inhibin, beta B
- domestic guinea pig(100719829) inhibin, beta B
- Goat(100861250) inhibin, beta B
- sheep(101119286) inhibin, beta B
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Anti-INHBB antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
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western blot