IL1R2
interleukin 1 receptor, type II
CD121b, CDw121b, IL-1R-2, IL-1RT-2, IL-1RT2, IL1R2c, IL1RB
Human IL1R2 (7850), Mouse Il1r2 (16178), Rat Il1r2 (117022), chicken IL1R2 (418715), dog IL1R2 (481330), cow IL1R2 (515700), domestic cat IL1R2 (101080961), domestic guinea pig Il1r2 (100723930), naked mole-rat Il1r2 (101710536), sheep IL1R2 (101103308)
- Human(7850) Summary: The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage. [provided by RefSeq, May 2012]
- Mouse(16178) interleukin 1 receptor, type II
- Rat(117022) interleukin 1 receptor, type II
- chicken(418715) interleukin 1 receptor, type II
- dog(481330) interleukin 1 receptor, type II
- cow(515700) interleukin 1 receptor, type II
- domestic cat(101080961) interleukin 1 receptor, type II
- domestic guinea pig(100723930) interleukin 1 receptor, type II
- naked mole-rat(101710536) interleukin 1 receptor, type II
- sheep(101103308) interleukin 1 receptor, type II
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